Philomena joins her older sister, Matilda Carmine Richie Pelphrey, whose name also includes Carmine. Cuoco and Pelphrey welcomed Matilda on March 30, 2023, and announced their engagement in August 2024. They later shared news of their second pregnancy through family photographs, including a cake with a pink interior. Those updates allowed followers to see selected milestones while the couple prepared for another child. The birth announcement continued that approach, sharing their happiness through a few personal images and a heartfelt caption.

Friends and admirers responded with congratulations as the couple celebrated their growing family. Cuoco, widely recognized for playing Penny on The Big Bang Theory and for her work in The Flight Attendant, placed the focus of the announcement on her daughters and partner. The photographs marked a personal milestone: welcoming Philomena, helping Matilda settle into being an older sister, and beginning life together as a family of four.